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A statistically significant network of interactions within the differentially regulated genes. The “Direct interaction” algorithm in MetaCore was used for generation of the interaction networks. Only genes with direct connections in the network are shown.

Journal: BMC Genomics

Article Title: Liver transcriptome analysis of Atlantic cod ( Gadus morhua ) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolism

doi: 10.1186/1471-2164-15-481

Figure Lengend Snippet: A statistically significant network of interactions within the differentially regulated genes. The “Direct interaction” algorithm in MetaCore was used for generation of the interaction networks. Only genes with direct connections in the network are shown.

Article Snippet: Analysis of the differentially regulated genes using the functional ontologies in MetaCore (GeneGo pathway map, process network and GO process) resulted in significant enrichment of many pathways and networks mainly related to lipid metabolism, cell cycle, tissue remodeling and wound repair, immune response, stress response, apoptosis and various signaling pathways (Table , Additional file : Tables S2-4).

Techniques: